Ing1 - inhibitor of growth family, member 1 Gene

Also Known as mING1h; p33Ing1; p37Ing1b; 2610028J21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26356

Summary

Predicted to enable methylated histone binding activity. Acts upstream of or within positive regulation of transcription, DNA-templated; protein import into nucleus; and regulation of cell death. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in head and neck squamous cell carcinoma and squamous cell carcinoma. Orthologous to human ING1 (inhibitor of growth family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Ing1 Products (6)

mRNA Protein Name
NM_001302451.1 NP_001289380.1 inhibitor of growth protein 1 isoform 2
NM_001302457.1 NP_001289386.1 inhibitor of growth protein 1 isoform 3
NM_001302458.1 NP_001289387.1 inhibitor of growth protein 1 isoform 3
NM_001302459.1 NP_001289388.1 inhibitor of growth protein 1 isoform 3
NM_001302460.1 NP_001289389.1 inhibitor of growth protein 1 isoform 3
NM_011919.5 NP_036049.2 inhibitor of growth protein 1 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16098148 MGI
acts upstream of or within protein import into nucleus IMP
IMP: Inferred from mutant phenotype
12054579 MGI
acts upstream of or within regulation of programmed cell death IMP
IMP: Inferred from mutant phenotype
12054579 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IMP
IMP: Inferred from mutant phenotype
12054579 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inhibitor of growth protein 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991646 ING-1 99.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06807 ING1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17453 Ing1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23909 Ing1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ing1 NCBI NCBI:3621