Zbtb1 - zinc finger and BTB domain containing 1 Gene

Also Known as Bsg2; 9430077A12; C430003J21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268564

Summary

Enables protein homodimerization activity. Involved in positive regulation of T cell mediated immunity; positive regulation of lymphocyte differentiation; and thymus development. Acts upstream of or within B cell differentiation and T cell differentiation in thymus. Predicted to be located in centrosome; nuclear body; and nuclear membrane. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; cerebral cortex; female reproductive system; trigeminal ganglion; and urinary system. Orthologous to human ZBTB1 (zinc finger and BTB domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb1 Products (2)

mRNA Protein Name
NM_001364323.1 NP_001351252.1 zinc finger and BTB domain-containing protein 1 isoform 2
NM_178744.3 NP_848859.1 zinc finger and BTB domain-containing protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18218630 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
22753936 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within B cell differentiation IMP
IMP: Inferred from mutant phenotype
22201126 MGI
acts upstream of or within T cell differentiation in thymus IMP
IMP: Inferred from mutant phenotype
22201126 MGI
involved in positive regulation of T cell differentiation IMP
IMP: Inferred from mutant phenotype
22201126 MGI
involved in positive regulation of T cell mediated immunity IDA
IDA: Inferred from direct assay
22753936 MGI
involved in positive regulation of natural killer cell differentiation IMP
IMP: Inferred from mutant phenotype
22753936 MGI
involved in positive regulation of pro-T cell differentiation IMP
IMP: Inferred from mutant phenotype
22753936 MGI
involved in thymus development IMP
IMP: Inferred from mutant phenotype
22201126 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 1

  • brain specific protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15959 ZBTB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19496 Zbtb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25990 Zbtb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zbtb1 NCBI NCBI:22890