Exo1 - exonuclease 1 Gene

Also Known as Msa; 5730442G03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26909

Summary

Enables chromatin binding activity. Acts upstream of or within humoral immune response mediated by circulating immunoglobulin; isotype switching; and somatic hypermutation of immunoglobulin genes. Predicted to be located in nuclear body and plasma membrane. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb segment; and nose. Orthologous to human EXO1 (exonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Exo1 Products (1)

mRNA Protein Name
NM_012012.4 NP_036142.2 exonuclease 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
14716311 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within humoral immune response mediated by circulating immunoglobulin IMP
IMP: Inferred from mutant phenotype
14716311 MGI
acts upstream of or within isotype switching IMP
IMP: Inferred from mutant phenotype
14716311 MGI
acts upstream of or within somatic hypermutation of immunoglobulin genes IMP
IMP: Inferred from mutant phenotype
14716311 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exonuclease 1

  • exonuclease I

  • mExo1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112670 Exo1 Modulator 99.77% Unkown
HY-174143 EXO1-IN-1 Inducer 99.00% Unkown
HY-P3187 exo-β-1,4-Xylosidase, Cellulosimicrobium cellulans sp. 21 / Unkown
HY-177512 MSC778 Inhibitor / Unkown
HY-170845 MU1409 Inhibitor 98.52% Unkown
HY-180573 ART5537 Inhibitor 99.84% Unkown
HY-162273 Antibacterial agent 189 Inhibitor / Unkown
HY-162274 Oxazepine / Unkown
HY-RS04585 EXO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175883 FEN1-IN-8 Inhibitor / Unkown
HY-RS20731 Exo1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27243 Exo1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Exo1 NCBI NCBI:9156