Nat8l - N-acetyltransferase 8-like Gene

Also Known as Shati; 1110038O08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 269642

Summary

Enables aspartate N-acetyltransferase activity. Involved in positive regulation of dopamine uptake involved in synaptic transmission. Located in endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; hemolymphoid system gland; intestine; lung; and retina. Orthologous to human NAT8L (N-acetyltransferase 8 like). [provided by Alliance of Genome Resources, Apr 2022]

Nat8l Products (1)

mRNA Protein Name
NM_001001985.3 NP_001001985.3 N-acetylaspartate synthetase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables aspartate N-acetyltransferase activity IDA
IDA: Inferred from direct assay
19807691 MGI
enables aspartate N-acetyltransferase activity IMP
IMP: Inferred from mutant phenotype
24155240 MGI
Biological Process GO Annotation Evidence References Source
involved in acetate metabolic process IGI
IGI: Inferred from genetic interaction
28077719 MGI
involved in aspartate metabolic process IGI
IGI: Inferred from genetic interaction
28077719 MGI
involved in positive regulation of dopamine uptake involved in synaptic transmission IDA
IDA: Inferred from direct assay
19014384 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
19807691 MGI
is active in mitochondrial matrix IDA
IDA: Inferred from direct assay
24155240 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acetylaspartate synthetase

  • N-acetyltransferase 8-like protein

  • NAA synthase

  • NAA synthetase

  • aspartate N-acetyltransferase

  • protein Shati

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09044 NAT8L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181719 NAT8L-IN-1 Inhibitor / Unkown
HY-181750 NAT8L-IN-2 / Unkown
HY-RS22671 Nat8l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29185 Nat8l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nat8l NCBI NCBI:339983