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Cat. No.: HY-181719

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NAT8L-IN-1

NAT8L-IN-1 is a NAT8L inhibitor with an IC₅₀ value of 0.3 μM. NAT8L-IN-1 can be used for the research of Canavan disease.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₂₀H₂₀ClN₃O₃S
Masse moléculaire:417.91

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

NAT8L-IN-1 Chemical Structure

Stock

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

NAT8L-IN-1 is a NAT8L inhibitor with an IC₅₀ value of 0.3 μM. NAT8L-IN-1 can be used for the research of Canavan disease^[1].

Voir tous les produits spécifiques à Isoform Acyltransferase :

In Vitro

NAT8L-IN-1 (compound 4t) exhibits high clearance in liver microsomes, with less than 5% remaining after incubation for 30 min in the presence of NADPH^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Masse moléculaire 417.91
Formule C₂₀H₂₀ClN₃O₃S
SMILES

O=C(N1CC(CC2=NC(C3=CSC=C3)=NO2)CCC1)COC4=CC=CC=C4Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Nayeen MJ, et al. Discovery of N-Acetyltransferase 8-Like (NAT8L) inhibitors based on a N-Acylated (Piperidin-3-ylmethyl)-1,2,4-Oxadiazole Scaffold. ACS Med Chem Lett. Published online February 3, 2026. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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NAT8L-IN-1

Voir tous les produits spécifiques à Isoform Acyltransferase