LAMP3 - lysosomal associated membrane protein 3 Gene

Homo sapiens

Also known as LAMP; CD208; DCLAMP; LAMP-3; TSC403; DC LAMP; DC-LAMP

Gene ID: 27074 | Gene type: protein coding

About LAMP3

Cytogenetic location: 3q27.1 Genomic coordinates (GRCh38): 3:183,122,215-183,163,813 (from NCBI)

This gene has 5 transcripts (splice variants) and 50 orthologues. Biased expression in lung (RPKM 74.1), appendix (RPKM 11.0) and 3 other tissues.

Summary

Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]

LAMP3 Products(1)

mRNA	Protein	Name
NM_014398.4	NP_055213.2	lysosome-associated membrane glycoprotein 3 precursor

LAMP3 Protein Structure

Lamp

0
100
200
300
416 a.a.

Protein Preferred Names

Protein Names

lysosome-associated membrane glycoprotein 3

DC-lysosome-associated membrane glycoprotein

Recombinant LAMP3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77435	LAMP3/CD208 Protein, Human (HEK293, His)	Q9UQV4/NP_055213.2 (K28-T381)	≥95%

Related Diseases

Diseases

Alias

Mumps

Parotitis Due To Mumps Virus	Mumps Nos
Epidemic Parotitis	Infectious Parotitis

Rem Sleep Behavior Disorder

Rapid Eye Movement Sleep Behavior Disorder	Rem Sleep Behaviour Disorder
Rapid Eye Movement Sleep Behaviour Disorder	Rem - [Rapid Eye Movement] Behaviour Disorder

Gaucher'S Disease

Gaucher Disease	Kerasin Thesaurismosis
Glucocerebrosidase Deficiency	Glucosylceramidase Deficiency
Cerebroside Lipidosis Syndrome	Acid Beta-Glucosidase Deficiency
Glucosylceramide Beta-Glucosidase Deficiency	Acute Cerebral Gaucher Disease
Gaucher Splenomegaly	Glucocerebrosidosis
Glucosyl Cerebroside Lipidosis	Kerasin Lipoidosis
Lipoid Histiocytosis	Glocucerebrosidase Deficiency
Sphingolipidosis 1	Gaucher Syndrome
Gauchers Disease	Gd
Glucosylceramide Lipidosis	Kerasin Histiocytosis
Gaucher Disease, Type 1	Gaucher Disease, Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07511	LAMP3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	LAMP3	VGNC	VGNC:30777
Rattus norvegicus	LAMP3	RGD	RGD:1307928
Felis catus	LAMP3	VGNC	VGNC:63187
Macaca mulatta	LAMP3	VGNC	VGNC:74045
Mus musculus	LAMP3	MGD	MGI:2441659
Others	LAMP3	NCBI

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