AMY1A - amylase alpha 1A Gene

Homo sapiens

Also known as AMY1

Gene ID: 276 | Gene type: protein coding

About AMY1A

Cytogenetic location: 1p21.1 Genomic coordinates (GRCh38): 1:103,655,519-103,664,554 (from NCBI)

This gene has 4 transcripts (splice variants), 192 orthologues and 7 paralogues. Restricted expression toward salivary gland (RPKM 4834.2).

Summary

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and Polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

AMY1A Products(2)

mRNA	Protein	Name
NM_001008221.1	NP_001008222.1	alpha-amylase 1A precursor
NM_004038.4	NP_004029.2	alpha-amylase 1A precursor

AMY1A Protein Structure

Alpha-amylase

Alpha-amylase_C

0
100
200
300
400
511 a.a.

Protein Preferred Names

Protein Names

alpha-amylase 1A

1,4-alpha-D-glucan glucanohydrolase 1

Related Diseases

Diseases

Alias

Dental Caries

Dental Caries Extending Into Pulp	Dental Caries Of Smooth Surface
Dental Caries Pit And Fissure	Smooth Surface Dental Caries
Dental Decay	Carious Teeth
Dental Cavity	Saprodontia
Teeth Decayed	Tooth Caries
Tooth Decay

Panic Disorder

Panic Anxiety Syndrome	Panic
Panic Disorder 1	Episodic Paroxysmal Anxiety Disorder

Alveolar Periostitis

Dry Socket	Alveolitis Of Jaw
Dry Tooth Socket	Alveolar Pyorrhea
Alveolar Osteitis	Alveolitis Sicca Dolorosa
Alveolodental Periostitis

Anxiety

Anxiety Disorder	Anxiety Disorders
Anxiety State	Anxieties
Anxiety Neurosis

Sick Building Syndrome

Avoidant Personality Disorder

Anxious Personality Disorder

Personality Disorders

Bruxism

Sleep Bruxism	Sleep-Related Bruxism
Bruxism - Teeth Grinding	Grinding Teeth
Sleep Related Bruxism	Teeth Grinding
Sleep Related Teeth Grinding

Phobic Disorder

Phobic Disorders

Phobic Anxiety Disorder

Social Phobia

Phobia, Social	Phobia Social
Phobic Anxiety Disorder

Post-Traumatic Stress Disorder

PTSD	Traumatic Neurosis
Post Traumatic Stress Disorder	Stress Disorders, Post-Traumatic
Posttraumatic Stress Disorder	Ptsd - [Post Traumatic Stress Disorder]
Trauma-Related Disorders

Stereotypic Movement Disorder

Stereotypy Habit Disorder	Stereotyped Repetitive Movements
Stereotyped Disorder	Stereotypes Nos
Stereotype Habit Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00672	AMY1A Human Pre-designed siRNA Set A		/	Unkown

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