Eif5a - eukaryotic translation initiation factor 5A Gene

Also Known as Eif4d; Eif5a1; eIF-4D; eIF-5A; eIF-5A1; eIF-5A-1; D19Wsu54e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 276770

Summary

This gene encodes an elongation initiation factor, which participates in protein synthesis. The encoded protein also plays roles in mRNA metabolism, cell proliferation, and cell cycle control. This protein contains a modified lysine residue called hypusine, which appears to be necessary for its function. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2, 5, and 19. [provided by RefSeq, Oct 2009]

Eif5a Products (9)

mRNA Protein Name
NM_001166589.1 NP_001160061.1 eukaryotic translation initiation factor 5A-1
NM_001166590.1 NP_001160062.1 eukaryotic translation initiation factor 5A-1
NM_001166591.1 NP_001160063.1 eukaryotic translation initiation factor 5A-1
NM_001166592.1 NP_001160064.1 eukaryotic translation initiation factor 5A-1
NM_001166593.1 NP_001160065.1 eukaryotic translation initiation factor 5A-1
NM_001166594.1 NP_001160066.1 eukaryotic translation initiation factor 5A-1
NM_001166595.1 NP_001160067.1 eukaryotic translation initiation factor 5A-1
NM_001166596.1 NP_001160068.1 eukaryotic translation initiation factor 5A-1
NM_181582.4 NP_853613.1 eukaryotic translation initiation factor 5A-1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
12894223 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12894223 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12894223 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 5A-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N2397 9''-Methyl salvianolate B 99.54% Unkown
HY-111522 RK-9123016 Inhibitor 99.65% Unkown
HY-106801 Girolline / Unkown
HY-RS04286 EIF5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W141446 VT00065 Inhibitor ≥98.0% Unkown
HY-121722 Deoxyhypusine / Unkown
HY-122039 Hypusine dihydrochloride / Unkown
HY-RS04285 EIF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04287 EIF5A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-126171 Hypusine / Unkown
HY-RS19060 Eif5a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19678 Eif5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25550 Eif5a2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26171 Eif5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif5a NCBI NCBI:1984