Larp7 - La ribonucleoprotein 7, transcriptional regulator Gene

Also Known as D3Wsu161e; C330027G06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 28036

Summary

Enables U6 snRNA binding activity. Involved in ncRNA metabolic process; regulation of mRNA splicing, via spliceosome; and spermatogenesis. Acts upstream of or within several processes, including germ cell proliferation; negative regulation of chromatin binding activity; and positive regulation of G1/S transition of mitotic cell cycle. Located in nucleus. Is expressed in several structures, including central nervous system; gonad; liver; sensory organ; and spleen. Orthologous to human LARP7 (La ribonucleoprotein 7, transcriptional regulator). [provided by Alliance of Genome Resources, Apr 2022]

Larp7 Products (1)

mRNA Protein Name
NM_138593.2 NP_613059.2 la-related protein 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables U6 snRNA binding IMP
IMP: Inferred from mutant phenotype
32017896 MGI
Biological Process GO Annotation Evidence References Source
involved in U6 2'-O-snRNA methylation IMP
IMP: Inferred from mutant phenotype
32017896 MGI
involved in box C/D sno(s)RNA 3'-end processing IMP
IMP: Inferred from mutant phenotype
32017896 MGI
acts upstream of or within germ cell proliferation IMP
IMP: Inferred from mutant phenotype
23154982 MGI
acts upstream of or within negative regulation of chromatin binding IGI
IGI: Inferred from genetic interaction
23154982 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
23154982 MGI
acts upstream of or within positive regulation of G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
23154982 MGI
involved in regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
32017896 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
32017896 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
32017896 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

la-related protein 7

  • La ribonucleoprotein domain family, member 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07531 LARP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20441 Larp7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26950 Larp7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Larp7 NCBI NCBI:51574