2. Gene
  3. CD28 - CD28 molecule Gene

CD28 - CD28 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus
Gene ID: 281050 | Gene type: protein coding

About CD28

Primary_assembly 2: 91,906,146-91,939,649 forward strand.ARS-UCD1.2:CM008169.2

This gene has 3 transcripts (splice variants), 132 orthologues and 1 paralogue.

CD28 Products(1)

mRNA Protein Name
NM_181004.1 NP_851347.1 T-cell-specific surface glycoprotein CD28 precursor

CD28 Protein Structure

Ig

Ig: cl11960 (44 - 159)

Ig

Ig: cd00096 (59 - 63)

Ig

Ig: cd00096 (75 - 79)

Ig

Ig: cd00096 (117 - 121)

Ig

Ig: cd00096 (131 - 136)

Ig

Ig: cd00096 (149 - 153)

  • 0
  • 100
  • 200
  • 243 a.a.
Protein Preferred Names Protein Names

T-cell-specific surface glycoprotein CD28

antigen CD28

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P1698 Reltecimod Antagonist 98.62% Phase 3
HY-P1698B Reltecimod TFA Chemical 99.78% Phase 3
Inhibitory Antibodies (12)
Cat. No. Product Name Effect
Purity Phase
HY-P9986 Tiragolumab Inhibitor 99.04% Phase 3
HY-P99961 Tifcemalimab Inhibitor 96.02% Phase 3
HY-P99293 Galiximab Inhibitor 99.23% Phase 3
HY-P99302 Lulizumab Inhibitor ≥95.0% Phase 2
HY-P99420 Acazicolcept Antagonist 99.27% Phase 2
HY-P990587 FR104 Inhibitor 97.26% Phase 2
HY-P99431 KY-1044 99.51% Phase 2
HY-P990773 Venanprubart Inhibitor 98.00% Phase 2
HY-P990079 Renvistobart Inhibitor 99.95% Phase 2
HY-P990752 Nezastomig / Phase 2
HY-P991176 RG-6333 Agonist 98.05% Phase 1
HY-P991183 SAR-442257 Inhibitor ≥99.0% Phase 1
Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-122822 GSK699 Activator 98.80% Unkown
HY-102090 B7/CD28 interaction inhibitor 1 99.81% Unkown
HY-100891 CD80-IN-3 98.02% Unkown
HY-19486 UR-1505 Inhibitor 99.97% Unkown
HY-179648 CD28-IN-2 Inhibitor / Unkown
HY-176265 DDS5 Inhibitor / Unkown
HY-175780 CD28-IN-1 Inhibitor / Unkown
HY-162810 ICOS-IN-1 / Unkown
HY-169819 Calcium influx inducer compound 634 Activator / Unkown
HY-N10446 Maydispenoid B / Unkown
HY-181507 CD28-IN-3 Inhibitor / Unkown
HY-N10445 Maydispenoid A / Unkown
HY-168384 M04 / Unkown
Inhibitory Antibodies (20)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9975 Theralizumab Agonist 99.46% Unkown
HY-P99123 Anti-Mouse CD28 Antibody (37.51) 95.00% Unkown
HY-P990865 Anti-CD28 Antibody (9.3) Inhibitor 99% Unkown
HY-P990136 Anti-Monkey/Human CD28 Antibody (CD28.2) Inhibitor 95.00% Unkown
HY-P991907 Anti-CD80 Antibody (TKMF5) 96.92% Unkown
HY-P990298 Anti-Mouse BTLA/CD272 Antibody (6A6) Inhibitor 95.00% Unkown
HY-P990237 Anti-Mouse ICOS Antibody (7E.17G9) Inhibitor 98% Unkown
HY-P991038 Zadoprubart 99% Unkown
HY-P992182 ANB032 Agonist / Unkown
HY-P992196 Anti-Canine CD28 Antibody (1C6) Inhibitor / Unkown
HY-P991835 Anti-Mouse BTLA/CD272 Antibody (PJ196) Inhibitor / Unkown
HY-P991833 Anti-Mouse BTLA/CD272 Antibody (PK18.6) Inhibitor / Unkown
HY-P99893 Rozibafusp alfa Inhibitor / Unkown
HY-P992125 Radanstobart Inhibitor / Unkown
HY-P990128 Anti-Rat CD80/B7-1 Antibody (3H5) Inhibitor / Unkown
HY-P990137 Anti-Rat CD28 Antibody (JJ319) Inhibitor / Unkown
HY-P990819 Anti-Rat CD28 Antibody (JJ316) Inhibitor / Unkown
HY-P990803 Anti-Mouse CD28 Antibody (PV-1) Inhibitor 96.63% Unkown
HY-P99123A Anti-Mouse CD28 (LALA-PG) Antibody (D665) Inhibitor / Unkown
HY-P990793 Anti-Mouse CD28 Antibody (D665) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CD28 NCBI NCBI:940
Canis familiaris CD28 NCBI NCBI:403646
Macaca fascicularis CD28 NCBI NCBI:102146670
Mus musculus CD28 NCBI NCBI:12487
Rattus norvegicus CD28 NCBI NCBI:25660
Macaca mulatta CD28 NCBI NCBI:705313