CD80-IN-3
Based on 1 Customer Validation
CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 486449-65-4
- Formula: C17H10FN3O3
- Molecular Weight:323.28
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 486449-65-4
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Appearance Solid
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Molecular Weight 323.28
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Formula C17H10FN3O3
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Color Light brown to yellow
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SMILES
FC1=C(NC=C2C3=NN(C4=CC=C(C(O)=O)C=C4)C2=O)C3=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 35.71 mg/mL (110.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0933 mL | 15.4665 mL | 30.9329 mL | 77.3323 mL |
| 5 mM | 0.6187 mL | 3.0933 mL | 6.1866 mL | 15.4665 mL | |
| 10 mM | 0.3093 mL | 1.5466 mL | 3.0933 mL | 7.7332 mL | |
| 15 mM | 0.2062 mL | 1.0311 mL | 2.0622 mL | 5.1555 mL | |
| 20 mM | 0.1547 mL | 0.7733 mL | 1.5466 mL | 3.8666 mL | |
| 25 mM | 0.1237 mL | 0.6187 mL | 1.2373 mL | 3.0933 mL | |
| 30 mM | 0.1031 mL | 0.5155 mL | 1.0311 mL | 2.5777 mL | |
| 40 mM | 0.0773 mL | 0.3867 mL | 0.7733 mL | 1.9333 mL | |
| 50 mM | 0.0619 mL | 0.3093 mL | 0.6187 mL | 1.5466 mL | |
| 60 mM | 0.0516 mL | 0.2578 mL | 0.5155 mL | 1.2889 mL | |
| 80 mM | 0.0387 mL | 0.1933 mL | 0.3867 mL | 0.9667 mL | |
| 100 mM | 0.0309 mL | 0.1547 mL | 0.3093 mL | 0.7733 mL |
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