Arid1b - AT-rich interaction domain 1B Gene

Also Known as 6A3-5; Smcf1; smcf-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 282546

Summary

Predicted to enable DNA-binding transcription factor activity. Predicted to contribute to nucleosome binding activity. Involved in cellular response to angiotensin and response to ischemia. Located in cytoplasm and nucleus. Used to study ischemia. Biomarker of hypertension and ischemia. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome; Coffin-Siris syndrome 1; intellectual disability; lung non-small cell carcinoma; and neuroblastoma. Orthologous to human ARID1B (AT-rich interaction domain 1B). [provided by Alliance of Genome Resources, Apr 2022]

Arid1b Products (5)

mRNA Protein Name
XM_039099697.1 XP_038955625.1 AT-rich interactive domain-containing protein 1B isoform X5
XM_039099688.1 XP_038955616.1 AT-rich interactive domain-containing protein 1B isoform X2
XM_039099696.1 XP_038955624.1 AT-rich interactive domain-containing protein 1B isoform X4
XM_039099692.1 XP_038955620.1 AT-rich interactive domain-containing protein 1B isoform X3
XM_039099685.1 XP_038955613.1 AT-rich interactive domain-containing protein 1B isoform X1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to angiotensin IEP
IEP: Inferred from expression pattern
14633620 RGD
involved in response to ischemia IEP
IEP: Inferred from expression pattern
14633620 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AT-rich interactive domain-containing protein 1B

  • AT rich interactive domain 1B (Swi1 like)

  • transcription factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00967 ARID1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19050 Arid1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25540 Arid1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arid1b NCBI NCBI:57492