Krt14 - keratin 14 Gene

Also Known as Ka14; Krt1-14

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287701

Summary

Predicted to enable keratin filament binding activity. Involved in epithelial cell differentiation; response to ionizing radiation; and response to zinc ion. Located in keratin filament. Biomarker of esophagus small cell carcinoma. Human ortholog(s) of this gene implicated in Naegeli-Franceschetti-Jadassohn syndrome; dermatopathia pigmentosa reticularis; and epidermolysis bullosa simplex. Orthologous to human KRT14 (keratin 14). [provided by Alliance of Genome Resources, Apr 2022]

Krt14 Products (1)

mRNA Protein Name
NM_001008751.2 NP_001008751.1 keratin, type I cytoskeletal 14

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in epithelial cell differentiation IDA
IDA: Inferred from direct assay
8950218 RGD
involved in response to ionizing radiation IEP
IEP: Inferred from expression pattern
12793764 RGD
involved in response to zinc ion IEP
IEP: Inferred from expression pattern
16140947 RGD
Cellular Component GO Annotation Evidence Références Source
located in keratin filament IDA
IDA: Inferred from direct assay
8950218 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

keratin, type I cytoskeletal 14

  • CK-14

  • K14

  • cytokeratin-14

  • keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)

  • keratin 14, type I

  • keratin complex 1, acidic, gene 14

  • type I keratin Ka14

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-179587 1,2,3-Triazole-PEG8-amine / Unkown
HY-179588 PROTAC BET Degrader-14 / Unkown
HY-179589 JQ-1 (carboxylic acid)-amine-PEG8-cyanogen Degrader / Unkown
HY-RS07437 KRT14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19703 Krt14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26198 Krt14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Krt14 NCBI NCBI:3861