Rnf10 - ring finger protein 10 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 288710

Summary

Enables transcription cis-regulatory region binding activity. Involved in positive regulation of transcription by RNA polymerase II; postsynapse to nucleus signaling pathway; and regulation of nervous system development. Located in nucleus. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic density membrane. Orthologous to human RNF10 (ring finger protein 10). [provided by Alliance of Genome Resources, Apr 2022]

Rnf10 Products (1)

mRNA Protein Name
NM_001011904.1 NP_001011904.1 RING finger protein 10

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
18941509 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of Schwann cell proliferation IDA
IDA: Inferred from direct assay
18941509 RGD
involved in positive regulation of myelination IMP
IMP: Inferred from mutant phenotype
18941509 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18941509 RGD
involved in postsynapse to nucleus signaling pathway IDA
IDA: Inferred from direct assay
26977767 RGD
involved in postsynapse to nucleus signaling pathway IEP
IEP: Inferred from expression pattern
26977767 RGD
involved in postsynapse to nucleus signaling pathway IMP
IMP: Inferred from mutant phenotype
26977767 RGD
Cellular Component GO Annotation Evidence References Source
is active in extrinsic component of postsynaptic density membrane IDA
IDA: Inferred from direct assay
26977767 RGD
is active in extrinsic component of postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
26977767 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26977767 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26977767 RGD
located in nucleus IDA
IDA: Inferred from direct assay
18941509 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RING finger protein 10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12034 RNF10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20483 Rnf10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26991 Rnf10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf10 NCBI NCBI:9921