Cartpt - CART prepropeptide Gene

Also Known as Cart

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29131

Summary

Predicted to enable neuropeptide hormone activity. Involved in several processes, including adult feeding behavior; circadian regulation of gene expression; and regulation of peptide hormone secretion. Located in extracellular space. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in obesity. Orthologous to human CARTPT (CART prepropeptide). [provided by Alliance of Genome Resources, Apr 2022]

Cartpt Products (1)

mRNA Protein Name
NM_017110.1 NP_058806.1 cocaine- and amphetamine-regulated transcript protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17064765 RGD
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
15908120 RGD
involved in adult feeding behavior IDA
IDA: Inferred from direct assay
9590691 RGD
involved in cellular response to starvation IDA
IDA: Inferred from direct assay
9590691 RGD
involved in circadian regulation of gene expression IDA
IDA: Inferred from direct assay
15680948 RGD
involved in negative regulation of appetite IDA
IDA: Inferred from direct assay
9590691 RGD
involved in negative regulation of glucagon secretion IDA
IDA: Inferred from direct assay
16443761 RGD
acts upstream of positive regulation of MAPK cascade IDA
IDA: Inferred from direct assay
15908120 RGD
acts upstream of positive regulation of protein kinase activity IDA
IDA: Inferred from direct assay
15908120 RGD
involved in regulation of insulin secretion IDA
IDA: Inferred from direct assay
16443761 RGD
involved in somatostatin secretion IDA
IDA: Inferred from direct assay
16443761 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
9590691 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cocaine- and amphetamine-regulated transcript protein

  • cocaine and amphetamine regulated transcript

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01935 CARTPT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21831 Cartpt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28348 Cartpt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cartpt NCBI NCBI:9607