Brd8 - bromodomain containing 8 Gene

Also Known as p120

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291691

Summary

Predicted to enable nuclear receptor coactivator activity and Thyroid Hormone Receptor binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of NuA4 Histone Acetyltransferase complex and Swr1 complex. Biomarker of colorectal adenocarcinoma. Orthologous to human BRD8 (bromodomain containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Brd8 Products (4)

mRNA Protein Name
NM_001008509.1 NP_001008509.1 bromodomain-containing protein 8 isoform 2
NM_001414410.1 NP_001401339.1 bromodomain-containing protein 8 isoform 1
NM_001008509.1 NP_001008509.1 bromodomain-containing protein 8 isoform 2
NM_001414410.1 NP_001401339.1 bromodomain-containing protein 8 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17014737 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bromodomain-containing protein 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148116 DN02 Inhibitor 98.68% Unkown
HY-RS01609 BRD8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17186 Brd8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23637 Brd8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brd8 NCBI NCBI:10902