Ptgir - prostaglandin I2 receptor Gene

Rattus norvegicus

Gene ID: 292661 | Gene type: protein coding

About Ptgir

Primary_assembly 1: 77,579,596-77,581,979 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 187 orthologues, 8 paralogues and is associated with 4 phenotypes. Biased expression in Lung (RPKM 46.2), Spleen (RPKM 3.8) and 7 other tissues.

Summary

Predicted to enable prostacyclin receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Predicted to act upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgir Products(1)

mRNA	Protein	Name
NM_001077644.1	NP_001071112.1	prostacyclin receptor

Ptgir Protein Structure

7tm_GPCRs

0
100
200
300
416 a.a.

Protein Preferred Names

Protein Names

prostacyclin receptor

PGI receptor	PGI2 receptor
prostaglandin I receptor (IP)	prostaglandin I2 (prostacyclin) receptor (IP)
prostanoid IP receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS11386	PTGIR Human Pre-designed siRNA Set A	/	Unkown
HY-RS11387	Ptgir Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS11388	Ptgir Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ptgir	NCBI	NCBI:5739

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