Ptgir - prostaglandin I2 receptor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292661

About Ptgir

Primary_assembly 1: 77,579,596-77,581,979 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 187 orthologues, 8 paralogues and is associated with 4 phenotypes. Biased expression in Lung (RPKM 46.2), Spleen (RPKM 3.8) and 7 other tissues.

Summary

Predicted to enable prostacyclin receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Predicted to act upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgir Products (1)

mRNA Protein Name
NM_001077644.1 NP_001071112.1 prostacyclin receptor

Ptgir Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (42 - 331)

7tm_GPCRs

7tm_GPCRs: cd14964 (44 - 68)

7tm_GPCRs

7tm_GPCRs: cd14964 (78 - 100)

7tm_GPCRs

7tm_GPCRs: cd14964 (121 - 143)

7tm_GPCRs

7tm_GPCRs: cd14964 (166 - 182)

7tm_GPCRs

7tm_GPCRs: cd14964 (209 - 232)

7tm_GPCRs

7tm_GPCRs: cd14964 (266 - 288)

7tm_GPCRs

7tm_GPCRs: cd14964 (298 - 323)

  • 0
  • 100
  • 200
  • 300
  • 416 a.a.
Protein Preferred Names Protein Names

prostacyclin receptor

  • PGI receptor

  • PGI2 receptor

  • prostaglandin I receptor (IP)

  • prostaglandin I2 (prostacyclin) receptor (IP)

  • prostanoid IP receptor

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptgir NCBI NCBI:5739