Ptgir - prostaglandin I2 receptor Gene
Species: Rattus norvegicus
About Ptgir
This gene has 2 transcripts (splice variants), 187 orthologues, 8 paralogues and is associated with 4 phenotypes. Biased expression in Lung (RPKM 46.2), Spleen (RPKM 3.8) and 7 other tissues.
Summary
Predicted to enable prostacyclin receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Predicted to act upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Apr 2022]
Ptgir Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001077644.1 | NP_001071112.1 | prostacyclin receptor |
Ptgir Protein Structure
7tm_GPCRs: cl28897 (42 - 331)
7tm_GPCRs: cd14964 (44 - 68)
7tm_GPCRs: cd14964 (78 - 100)
7tm_GPCRs: cd14964 (121 - 143)
7tm_GPCRs: cd14964 (166 - 182)
7tm_GPCRs: cd14964 (209 - 232)
7tm_GPCRs: cd14964 (266 - 288)
7tm_GPCRs: cd14964 (298 - 323)
- 0
- 100
- 200
- 300
- 416 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
prostacyclin receptor |
|
|