Adora1 - adenosine A1 receptor Gene

Rattus norvegicus

Gene ID: 29290 | Gene type: protein coding

About Adora1

Primary_assembly 13: 45,658,872-45,695,801 reverse strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 274 orthologues, 3 paralogues and is associated with 36 phenotypes. Biased expression in Brain (RPKM 184.), Spleen (RPKM 61.9) and 8 other tissues.

Summary

Enables several functions, including G protein-coupled Adenosine Receptor activity; G-protein beta/gamma-subunit complex binding activity; and heterotrimeric G-protein binding activity. Involved in several processes, including lipid homeostasis; modulation of chemical synaptic transmission; and regulation of secretion. Located in several cellular components, including axon; basolateral plasma membrane; and synaptic membrane. Is active in calyx of Held. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Used to study cerebral infarction; hypertension; lung disease; and obstructive sleep apnea. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADORA1 (adenosine A1 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Adora1 Products(1)

mRNA	Protein	Name
NM_017155.3	NP_058851.2	adenosine receptor A1

Adora1 Protein Structure

7tmA_Adenosine_R_A1

0
100
200
300
326 a.a.

Protein Preferred Names

Protein Names

adenosine receptor A1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS00391	ADORA1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS00392	Adora1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS00393	Adora1 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adora1	NCBI	NCBI:134

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