Pax2 - paired box 2 Gene

Also Known as Pax-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 293992

Summary

Predicted to enable C2H2 zinc finger domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including aging; cellular response to epidermal growth factor stimulus; and positive regulation of cell population proliferation. Located in lysosome and nucleus. Biomarker of nephroblastoma. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 7 and renal coloboma syndrome. Orthologous to human PAX2 (paired box 2). [provided by Alliance of Genome Resources, Apr 2022]

Pax2 Products (1)

mRNA Protein Name
NM_001106361.1 NP_001099831.1 paired box protein Pax-2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to epidermal growth factor stimulus IEP
IEP: Inferred from expression pattern
11262416 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15569307 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
18639218 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired box protein Pax-2

  • paired box gene 2

  • paired box homeotic gene 2

  • paired box protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124838 EG1 98.26% Unkown
HY-RS10089 PAX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174561 Human PAX2 mRNA / Unkown
HY-RS22268 Pax2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28791 Pax2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pax2 NCBI NCBI:5076