Hexb - hexosaminidase subunit beta Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 294673

Summary

Enables beta-N-acetylglucosaminidase activity; carbohydrate binding activity; and identical protein binding activity. Involved in N-acetylglucosamine metabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in Sandhoff disease and spinal muscular atrophy. Orthologous to human HEXB (hexosaminidase subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Hexb Products (1)

mRNA Protein Name
NM_001011946.2 NP_001011946.1 beta-hexosaminidase subunit beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables beta-N-acetylglucosaminidase activity IDA
IDA: Inferred from direct assay
1397486 RGD
enables carbohydrate binding IDA
IDA: Inferred from direct assay
8702598 RGD
enables hexosaminidase activity IDA
IDA: Inferred from direct assay
8702598 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
1397486 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
1397486 RGD
Biological Process GO Annotation Evidence References Source
involved in N-acetylglucosamine metabolic process IDA
IDA: Inferred from direct assay
1397486 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-hexosaminidase subunit beta

  • N-acetyl-beta-glucosaminidase subunit beta

  • beta-N-acetylhexosaminidase subunit beta

  • hexosaminidase B

  • hexosaminidase subunit B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-104050 M-31850 99.79% Unkown
HY-108241A Galacto-PUGNAc Inhibitor / Unkown
HY-175076 Globotriaosylceramide (non-hydroxy) (porcine RBC) / Unkown
HY-RS06143 HEXB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N12056 Cyclo(L-leucyl-L-valyl) 99.35% Unkown
HY-RS18135 Hexb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24610 Hexb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hexb NCBI NCBI:3074