Amhr2 - anti-Mullerian hormone receptor type 2 Gene

Also Known as C14; MRII; MISRII

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29530

About Amhr2

Primary_assembly 7: 133,579,393-133,588,258 forward strand.mRatBN7.2:CM026980.1

This gene has 2 transcripts (splice variants), 179 orthologues, 11 paralogues and is associated with 11 phenotypes. Biased expression in Testes (RPKM 16.1), Heart (RPKM 38.7) and 6 other tissues.

Summary

Enables transforming growth factor beta receptor activity, type II. Involved in female gonad development and male gonad development. Acts upstream of or within transforming growth factor beta receptor signaling pathway. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in persistent Mullerian duct syndrome. Orthologous to human AMHR2 (anti-Mullerian hormone receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]

Amhr2 Products (1)

mRNA Protein Name
NM_030998.2 NP_112260.1 anti-Muellerian hormone type-2 receptor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transforming growth factor beta receptor activity, type II IDA
IDA: Inferred from direct assay
11376112 RGD
Biological Process GO Annotation Evidence References Source
involved in female gonad development IEP
IEP: Inferred from expression pattern
8119126 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
8119126 RGD
acts upstream of or within transforming growth factor beta receptor signaling pathway IDA
IDA: Inferred from direct assay
11376112 RGD
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
11376112 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Amhr2 Protein Structure

LU

LU: cl10471 (60 - 118)

PKc_like

PKc_like: cl21453 (204 - 505)

  • 0
  • 100
  • 200
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  • 400
  • 500
  • 557 a.a.
Protein Preferred Names Protein Names

anti-Muellerian hormone type-2 receptor

  • AMH type II receptor

  • MIS type II receptor

  • anti-Muellerian hormone type II receptor

  • anti-Mullerian hormone receptor type 11 SV1

  • anti-Mullerian hormone receptor, type II

  • anti-Mullerian hormone type 2 receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00654 AMHR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00655 Amhr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00656 Amhr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174780 Human AMHR2 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amhr2 NCBI NCBI:269