Amhr2 - anti-Mullerian hormone receptor type 2 Gene

Rattus norvegicus

Also known as C14; MRII; MISRII

Gene ID: 29530 | Gene type: protein coding

About Amhr2

Primary_assembly 7: 133,579,393-133,588,258 forward strand.mRatBN7.2:CM026980.1

This gene has 2 transcripts (splice variants), 179 orthologues, 11 paralogues and is associated with 11 phenotypes. Biased expression in Testes (RPKM 16.1), Heart (RPKM 38.7) and 6 other tissues.

Summary

Enables transforming growth factor beta receptor activity, type II. Involved in female gonad development and male gonad development. Acts upstream of or within transforming growth factor beta receptor signaling pathway. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in persistent Mullerian duct syndrome. Orthologous to human AMHR2 (anti-Mullerian hormone receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]

Amhr2 Products(1)

mRNA	Protein	Name
NM_030998.2	NP_112260.1	anti-Muellerian hormone type-2 receptor precursor

Amhr2 Protein Structure

PKc_like

0
100
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300
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500
557 a.a.

Protein Preferred Names

Protein Names

anti-Muellerian hormone type-2 receptor

AMH type II receptor	MIS type II receptor
anti-Muellerian hormone type II receptor	anti-Mullerian hormone receptor type 11 SV1
anti-Mullerian hormone receptor, type II	anti-Mullerian hormone type 2 receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS00654	AMHR2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS00655	Amhr2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS00656	Amhr2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Amhr2	NCBI	NCBI:269
Macaca fascicularis	Amhr2	NCBI	NCBI:102117592
Mus musculus	Amhr2	NCBI	NCBI:110542
Macaca mulatta	Amhr2	NCBI	NCBI:702822

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