Slc16a7 - solute carrier family 16 member 7 Gene

Also Known as Mct2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29735

About Slc16a7

Primary_assembly 7: 61,051,167-61,154,994 reverse strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 254 orthologues, 13 paralogues and is associated with 1 phenotype. Biased expression in Kidney (RPKM 249.5), Liver (RPKM 113.8) and 8 other tissues.

Summary

Predicted to enable lactate transmembrane transporter activity and pyruvate transmembrane transporter activity. Involved in plasma membrane lactate transport. Located in cytoplasm and plasma membrane. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and parallel fiber to Purkinje cell synapse. Is integral component of postsynaptic density membrane. Orthologous to human SLC16A7 (solute carrier family 16 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc16a7 Products (1)

mRNA Protein Name
NM_017302.2 NP_058998.2 monocarboxylate transporter 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15917240 RGD
enables symporter activity IDA
IDA: Inferred from direct assay
10417314 RGD
Biological Process GO Annotation Evidence References Source
involved in plasma membrane lactate transport IDA
IDA: Inferred from direct assay
19929853 RGD
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
15749979 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
15749979 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
15749979 RGD
is active in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
15749979 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
15749979 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Slc16a7 Protein Structure

2A0113

2A0113: TIGR00892 (20 - 435)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 489 a.a.
Protein Preferred Names Protein Names

monocarboxylate transporter 2

  • MCT 2

  • solute carrier family 16 (monocarboxylate transporter), member 7

  • solute carrier family 16 (monocarboxylic acid transporters), member 7

  • solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13030 Slc16a7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13029 SLC16A7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13031 Slc16a7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc16a7 NCBI NCBI:9194