2. Gene
  3. Mknk2 - MAPK interacting serine/threonine kinase 2 Gene

Mknk2 - MAPK interacting serine/threonine kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 299618 | Gene type: protein coding

About Mknk2

Primary_assembly 7: 9,039,728-9,050,827 forward strand.mRatBN7.2:CM026980.1

This gene has 2 transcripts (splice variants), 224 orthologues, 6 paralogues and is associated with 1 phenotype. Biased expression in Muscle (RPKM 36.3), Spleen (RPKM 34.2) and 9 other tissues.

Summary

Predicted to enable ATP binding activity; Calmodulin binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to arsenic-containing substance; intracellular signal transduction; and protein phosphorylation. Predicted to act upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mknk2 Products(1)

mRNA Protein Name
NM_001011985.2 NP_001011985.1 MAP kinase-interacting serine/threonine-protein kinase 2

Mknk2 Protein Structure

PKc_like

PKc_like: cl21453 (80 - 367)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 459 a.a.
Protein Preferred Names Protein Names

MAP kinase-interacting serine/threonine-protein kinase 2

MAP kinase signal-integrating kinase 2

MAP kinase-interacting serine/threonine kinase 2

MAPK signal-integrating kinase 2

mnk2

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-136848 SM1-71 Inhibitor 96.00% Unkown
HY-148062 RSS0680 98.03% Unkown
HY-RS08476 MKNK2 Human Pre-designed siRNA Set A / Unkown
HY-RS08477 Mknk2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08478 Mknk2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mknk2 NCBI NCBI:2872