Mknk2 - MAPK interacting serine/threonine kinase 2 Gene
Species: Rattus norvegicus
About Mknk2
This gene has 2 transcripts (splice variants), 224 orthologues, 6 paralogues and is associated with 1 phenotype. Biased expression in Muscle (RPKM 36.3), Spleen (RPKM 34.2) and 9 other tissues.
Summary
Predicted to enable ATP binding activity; Calmodulin binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to arsenic-containing substance; intracellular signal transduction; and protein phosphorylation. Predicted to act upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
Mknk2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001011985.2 | NP_001011985.1 | MAP kinase-interacting serine/threonine-protein kinase 2 |
Mknk2 Protein Structure
PKc_like: cl21453 (80 - 367)
- 0
- 100
- 200
- 300
- 400
- 459 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
MAP kinase-interacting serine/threonine-protein kinase 2 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-136848 | SM1-71 | Inhibitor | 96.09% | Unkown |
| HY-148062 | RSS0680 | Degrader | 99.85% | Unkown |
| HY-121723 | PU-H39 | Inhibitor | / | Unkown |
| HY-184652 | LRRK2/JNK3-IN-1 | Inhibitor | / | Unkown |
| HY-RS08476 | MKNK2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS08477 | Mknk2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS08478 | Mknk2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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