Eif4b - eukaryotic translation initiation factor 4B Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 300253

Summary

Predicted to enable RNA strand annealing activity; RNA strand-exchange activity; and ribosomal small subunit binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Located in dendrite and neuronal cell body. Is active in postsynapse. Orthologous to human EIF4B (eukaryotic translation initiation factor 4B). [provided by Alliance of Genome Resources, Apr 2022]

Eif4b Products (1)

mRNA Protein Name
NM_001008324.2 NP_001008325.1 eukaryotic translation initiation factor 4B

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
25332164 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
25332164 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 4B

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-129239 Farudodstat 99.68% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04273 EIF4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17097 Eif4b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23541 Eif4b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif4b NCBI NCBI:1975