Pla2g7 - phospholipase A2 group VII Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 301265

Summary

Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent Phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in several processes, including glycerophospholipid catabolic process; plasma lipoprotein particle remodeling; and positive regulation of monocyte chemotaxis. Located in cytoplasm and extracellular space. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Orthologous to human PLA2G7 (Phospholipase A2 group VII). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g7 Products (1)

mRNA Protein Name
NM_001009353.1 NP_001009353.1 platelet-activating factor acetylhydrolase precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
8692015 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet-activating factor acetylhydrolase

  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18540 KT109 Inhibitor 99.86% Unkown
HY-RS10634 PLA2G7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16659 Pla2g7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23094 Pla2g7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g7 NCBI NCBI:7941