Lig3 - DNA ligase 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303369

Summary

Enables DNA Ligase activity. Involved in base-excision repair, DNA ligation. Located in nucleus. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human LIG3 (DNA Ligase 3). [provided by Alliance of Genome Resources, Apr 2022]

Lig3 Products (2)

mRNA Protein Name
NM_001394035.1 NP_001380964.1 DNA ligase 3 isoform 1
NM_001394036.1 NP_001380965.1 DNA ligase 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA ligase activity IDA
IDA: Inferred from direct assay
17412650 RGD
Biological Process GO Annotation Evidence References Source
involved in base-excision repair, DNA ligation IDA
IDA: Inferred from direct assay
17412650 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA ligase 3

  • DNA ligase (ATP) 3

  • ligase III, DNA, ATP-dependent

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07643 LIG3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07789 LRIG3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22220 Lig3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28742 Lig3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991208 Flt-3L-Ig (hum/hum) 98% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lig3 NCBI NCBI:3980