Smarce1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 Gene

Also Known as BAF57; RGD1304726

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303518

Summary

Enables protein N-terminus binding activity. Involved in brain development; negative regulation of transcription, DNA-templated; and spermatid development. Located in nucleus. Human ortholog(s) of this gene implicated in familial meningioma. Orthologous to human SMARCE1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1). [provided by Alliance of Genome Resources, Apr 2022]

Smarce1 Products (2)

mRNA Protein Name
NM_001024993.2 NP_001020164.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform 2
NM_001399629.1 NP_001386558.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22215678 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
12192000 RGD
involved in spermatid development IEP
IEP: Inferred from expression pattern
22215678 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

  • BRG1-associated factor 57

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13415 SMARCE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20649 Smarce1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27160 Smarce1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smarce1 NCBI NCBI:6605