Cldn4 - claudin 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 304407

Summary

Predicted to enable Chloride Channel activity. Involved in circadian rhythm; female pregnancy; and response to progesterone. Located in several cellular components, including apicolateral plasma membrane; basal plasma membrane; and lateral plasma membrane. Biomarker of peptic esophagitis. Human ortholog(s) of this gene implicated in ovarian Cancer and pancreatic Cancer. Orthologous to human CLDN4 (Claudin 4). [provided by Alliance of Genome Resources, Apr 2022]

Cldn4 Products (1)

mRNA Protein Name
NM_001012022.1 NP_001012022.1 claudin-4

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
20091493 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
19555995 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
19555995 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17375208 RGD
located in apicolateral plasma membrane IDA
IDA: Inferred from direct assay
15068973 RGD
located in basal plasma membrane IDA
IDA: Inferred from direct assay
15447685 RGD
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
17375208 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

claudin-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02772 CLDN4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P11785 Cpe30 MT2 Ligand / Unkown
HY-RS21532 Cldn4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28050 Cldn4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cldn4 NCBI NCBI:1364