Pbx1 - PBX homeobox 1 Gene

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in animal organ development; neuron development; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including animal organ development; positive regulation of G2/M transition of mitotic cell cycle; and regionalization. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human PBX1 (PBX homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]