Gpr4 - G protein-coupled receptor 4 Gene

Rattus norvegicus

Gene ID: 308408 | Gene type: protein coding

About Gpr4

Primary_assembly 1: 78,865,409-78,876,599 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 141 orthologues and 14 paralogues. Biased expression in Heart (RPKM 15.7), Lung (RPKM 12.4) and 9 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and response to acidic pH. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; blood vessel development; and negative regulation of angiogenesis. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human GPR4 (G protein-coupled receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Gpr4 Products(1)

mRNA	Protein	Name
NM_001025680.1	NP_001020851.1	G-protein coupled receptor 4

Gpr4 Protein Structure

7tmA_GPR4

0
100
200
300
365 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-101784	NE 52-QQ57		99.89%	Unkown
HY-101536	GPR4 antagonist 1	Antagonist	98.92%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpr4	NCBI	NCBI:2828

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