Gpr4 - G protein-coupled receptor 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 308408

About Gpr4

Primary_assembly 1: 78,865,409-78,876,599 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 141 orthologues and 14 paralogues. Biased expression in Heart (RPKM 15.7), Lung (RPKM 12.4) and 9 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and response to acidic pH. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; blood vessel development; and negative regulation of angiogenesis. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human GPR4 (G protein-coupled receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Gpr4 Products (1)

mRNA Protein Name
NM_001025680.1 NP_001020851.1 G-protein coupled receptor 4

Gpr4 Protein Structure

7tmA_GPR4

7tmA_GPR4: cd15366 (19 - 46)

7tmA_GPR4

7tmA_GPR4: cd15366 (19 - 298)

7tmA_GPR4

7tmA_GPR4: cd15366 (53 - 78)

7tmA_GPR4

7tmA_GPR4: cd15366 (91 - 121)

7tmA_GPR4

7tmA_GPR4: cd15366 (133 - 155)

7tmA_GPR4

7tmA_GPR4: cd15366 (179 - 208)

7tmA_GPR4

7tmA_GPR4: cd15366 (218 - 248)

7tmA_GPR4

7tmA_GPR4: cd15366 (266 - 291)

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  • 300
  • 365 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101784 NE 52-QQ57 99.80% Unkown
HY-101536 GPR4 antagonist 1 Antagonist 98.92% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr4 NCBI NCBI:2828