Lmcd1 - LIM and cysteine-rich domains 1 Gene

Also Known as dyxin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30937

Summary

Enables transcription corepressor activity. Involved in positive regulation of calcineurin-NFAT signaling cascade and regulation of cardiac muscle hypertrophy. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and lung. Orthologous to human LMCD1 (LIM and cysteine rich domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Lmcd1 Products (1)

mRNA Protein Name
NM_144799.3 NP_659048.1 LIM and cysteine-rich domains protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16199866 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
16199866 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
16199866 MGI
involved in positive regulation of calcineurin-NFAT signaling cascade IMP
IMP: Inferred from mutant phenotype
20026769 MGI
involved in regulation of cardiac muscle hypertrophy IMP
IMP: Inferred from mutant phenotype
20026769 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
16199866 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LIM and cysteine-rich domains protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07710 LMCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19705 Lmcd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26201 Lmcd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lmcd1 NCBI NCBI:29995