Mef2a - myocyte enhancer factor 2a Gene
Species: Rattus norvegicus
Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including cellular response to calcium ion; cellular response to glucose stimulus; and dendrite morphogenesis. Located in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A). [provided by Alliance of Genome Resources, Apr 2022]
Mef2a Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001014035.2 | NP_001014057.1 | myocyte-specific enhancer factor 2A |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables DNA-binding transcription factor activity, RNA polymerase II-specific |
IDA
IDA: Inferred from direct assay
|
10521511 | RGD |
| enables sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
10521511 | RGD |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cellular response to calcium ion |
IDA
IDA: Inferred from direct assay
|
10521511 | RGD |
| involved in cellular response to glucose stimulus |
IEP
IEP: Inferred from expression pattern
|
18413674 | RGD |
| involved in dendrite morphogenesis |
IMP
IMP: Inferred from mutant phenotype
|
16484498 | RGD |
| involved in positive regulation of DNA-templated transcription |
IMP
IMP: Inferred from mutant phenotype
|
17696759 | RGD |
| involved in positive regulation of transcription by RNA polymerase II |
IDA
IDA: Inferred from direct assay
|
10521511 | RGD |
| involved in positive regulation of transcription by RNA polymerase II |
IMP
IMP: Inferred from mutant phenotype
|
26240138 | RGD |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
17696759 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
myocyte-specific enhancer factor 2A |
|