Cntfr - ciliary neurotrophic factor receptor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 313173

Summary

Enables ciliary neurotrophic factor receptor activity and cytokine binding activity. Predicted to be involved in ciliary neurotrophic factor-mediated signaling pathway. Predicted to act upstream of or within several processes, including brainstem development; negative regulation of neuron apoptotic process; and suckling behavior. Predicted to be located in apical plasma membrane. Predicted to be part of CNTFR-CLCF1 complex and ciliary neurotrophic factor receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human CNTFR (ciliary neurotrophic factor receptor). [provided by Alliance of Genome Resources, Apr 2022]

Cntfr Products (1)

mRNA Protein Name
NM_001003929.1 NP_001003929.1 ciliary neurotrophic factor receptor subunit alpha precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables ciliary neurotrophic factor receptor activity IMP
IMP: Inferred from mutant phenotype
8381290 RGD
enables cytokine binding IPI
IPI: Inferred from physical interaction
1648265 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ciliary neurotrophic factor receptor subunit alpha

  • CNTF receptor subunit alpha

  • CNTFR-alpha

  • ciliary neurotrophic factor receptor alpha

Recombinant Cntfr Proteins

Cat. No. Product Name Accession Purity
HY-P76276 CNTFR alpha Protein, Rat (sf9, His) Q08406 (Q23-P346) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02924 CNTFR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18513 Cntfr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24995 Cntfr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991945 Anti-CNTFR Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cntfr NCBI NCBI:1271