Errfi1 - ERBB receptor feedback inhibitor 1 Gene

Also Known as Xxx; Ralt; gene 33; RGD1307599

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 313729

Summary

Enables SH3 domain binding activity; kinase binding activity; and small GTPase binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to hormone stimulus; and negative regulation of macromolecule metabolic process. Located in cytosol and plasma membrane. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Errfi1 Products (1)

mRNA Protein Name
NM_001014071.1 NP_001014093.1 ERBB receptor feedback inhibitor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables SH3 domain binding IDA
IDA: Inferred from direct assay
11003669 RGD
enables kinase binding IPI
IPI: Inferred from physical interaction
17599051 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10749885 RGD
enables small GTPase binding IPI
IPI: Inferred from physical interaction
10749885 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular hyperosmotic response IEP
IEP: Inferred from expression pattern
10749885 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: Inferred from expression pattern
23384834 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: Inferred from expression pattern
15556944 RGD
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
15358516 RGD
involved in cellular response to platelet-derived growth factor stimulus IEP
IEP: Inferred from expression pattern
15556944 RGD
involved in negative regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
19204184 RGD
involved in negative regulation of cardiac muscle hypertrophy in response to stress IDA
IDA: Inferred from direct assay
19204184 RGD
involved in negative regulation of collagen biosynthetic process IMP
IMP: Inferred from mutant phenotype
19204184 RGD
involved in negative regulation of epidermal growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19204184 RGD
involved in negative regulation of epidermal growth factor-activated receptor activity IDA
IDA: Inferred from direct assay
17599051 RGD
involved in negative regulation of interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
19204184 RGD
involved in negative regulation of peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
17599051 RGD
involved in negative regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
19204184 RGD
involved in regulation of type B pancreatic cell proliferation IMP
IMP: Inferred from mutant phenotype
23384834 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ERBB receptor feedback inhibitor 1

  • gene 33 polypeptide

  • mig-6

  • mitogen-inducible gene 6 protein homolog

  • receptor-associated late transducer

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04516 ERRFI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19775 Errfi1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26272 Errfi1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Errfi1 NCBI NCBI:54206