1. Gene
  2. Zhx2 - zinc fingers and homeoboxes 2 Gene

Zhx2 - zinc fingers and homeoboxes 2 Gene

Rattus norvegicus
Gene ID: 314988 | Gene type: protein coding

About Zhx2

Primary_assembly 7: 89,226,463-89,374,378 forward strand.mRatBN7.2:CM026980.1

This gene has 4 transcripts (splice variants), 237 orthologues, 3 paralogues and is associated with 2 phenotypes. Biased expression in Muscle (RPKM 82.), Kidney (RPKM 75.5) and 9 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and retinal bipolar neuron differentiation. Predicted to act upstream of or within mRNA catabolic process; negative regulation of neuron differentiation; and somatic stem cell population maintenance. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZHX2 (zinc fingers and homeoboxes 2). [provided by Alliance of Genome Resources, Apr 2022]

Zhx2 Products(1)

mRNA Protein Name
NM_001271056.1 NP_001257985.1 zinc fingers and homeoboxes protein 2

Zhx2 Protein Structure

zf_C2H2_ZHX

zf_C2H2_ZHX: pfam18387 (105 - 157)

homeodomain

homeodomain: cd00086 (271 - 320)

homeodomain

homeodomain: cd00086 (443 - 495)

HOX

HOX: smart00389 (536 - 581)

homeodomain

homeodomain: cd00086 (635 - 683)

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  • 836 a.a.
Protein Preferred Names Protein Names

zinc fingers and homeoboxes protein 2

AFP regulator 1

alpha-fetoprotein regulator 1

regulator of AFP

transcription factor ZHX2

zinc finger and homeodomain protein 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Zhx2 NCBI NCBI:22882