Arsa - arylsulfatase A Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315222

Summary

Enables arylsulfatase activity. Involved in several processes, including response to estrogen; response to ethanol; and response to methylmercury. Located in cytoplasmic vesicle; extracellular space; and lysosome. Is extrinsic component of external side of plasma membrane. Used to study hypothyroidism. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human ARSA (arylsulfatase A). [provided by Alliance of Genome Resources, Apr 2022]

Arsa Products (1)

mRNA Protein Name
NM_001034933.3 NP_001030105.2 arylsulfatase A precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables arylsulfatase activity IDA
IDA: Inferred from direct assay
1363453 RGD
Biological Process GO Annotation Evidence References Source
involved in autophagy IDA
IDA: Inferred from direct assay
8037 RGD
involved in response to estrogen IDA
IDA: Inferred from direct assay
15040 RGD
involved in response to ethanol IDA
IDA: Inferred from direct assay
17067361 RGD
involved in response to methylmercury IDA
IDA: Inferred from direct assay
1682910 RGD
involved in response to nutrient IDA
IDA: Inferred from direct assay
4403 RGD
involved in response to pH IDA
IDA: Inferred from direct assay
6137211 RGD
Cellular Component GO Annotation Evidence References Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
15503159 RGD
located in endosome IDA
IDA: Inferred from direct assay
15503159 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
15503159 RGD
located in extrinsic component of external side of plasma membrane IDA
IDA: Inferred from direct assay
15503159 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arylsulfatase A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123650 FSBA hydrochloride 99.06% Unkown
HY-RS01034 ARSA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18745 Arsa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25232 Arsa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arsa NCBI NCBI:410
Mus musculus Arsa NCBI NCBI:11883