Nono - non-POU domain containing, octamer-binding Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 317259

Summary

Predicted to enable chromatin binding activity and identical protein binding activity. Involved in circadian rhythm. Predicted to be located in fibrillar center; nuclear matrix; and paraspeckles. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 34. Orthologous to human NONO (non-POU domain containing octamer binding). [provided by Alliance of Genome Resources, Apr 2022]

Nono Products (1)

mRNA Protein Name
NM_001012356.1 NP_001012356.1 non-POU domain-containing octamer-binding protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables lncRNA binding IDA
IDA: Inferred from direct assay
30566058 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15860628 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to angiotensin IMP
IMP: Inferred from mutant phenotype
30566058 RGD
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
32424772 RGD
involved in circadian rhythm IMP
IMP: Inferred from mutant phenotype
15860628 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
32424772 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

non-POU domain-containing octamer-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153918 (R)-SKBG-1 Inhibitor 99.68% Unkown
HY-153918A (S)-SKBG-1 99.01% Unkown
HY-RS09425 NONO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18626 Nono Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25112 Nono Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991327 PAT-LM1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nono NCBI NCBI:4841