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  3. HOXA4 - homeobox A4 Gene

HOXA4 - homeobox A4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HOX1; HOX1D

Gene ID: 3201 | Gene type: protein coding

About HOXA4

Cytogenetic location: 7p15.2 Genomic coordinates (GRCh38): 7:27,128,525-27,130,757 (from NCBI)

This gene has 4 transcripts (splice variants), 188 orthologues and 42 paralogues. Broad expression in esophagus (RPKM 4.4), lung (RPKM 4.1) and 19 other tissues.

Summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]

HOXA4 Products(1)

mRNA Protein Name
NM_002141.5 NP_002132.3 homeobox protein Hox-A4

HOXA4 Protein Structure

Homeobox

Homeobox: Homeobox domain (216 - 272)

  • 0
  • 100
  • 200
  • 300
  • 320 a.a.
Protein Preferred Names Protein Names

homeobox protein Hox-A4

Dfd-like protein

Related Diseases

Diseases Alias
Athabaskan Brainstem Dysgenesis Syndrome

Bosley-Salih-Alorainy Syndrome

Navajo Brainstem Syndrome

ABDS

Human Hoxa1 Syndromes

BSAS

Athabaskan Brainstem Dysgenesis

Bosley Salih Alorainy Syndrome

Absd

Athabascan Brainstem Dysgenesis Syndrome

Narvajo Brainstem Syndrome
Hypospadias

Hypospadias Familial

Familial Hypospadias
Hand-Foot-Genital Syndrome

Hand-Foot-Uterus Syndrome

Hfgs

Hfg Syndrome

Hfu Syndrome

HFG

Hfu

Hand Foot Uterus Syndrome

Hand Foot Genital Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06299 HOXA4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris HOXA4 VGNC VGNC:41748
Mus musculus HOXA4 MGD MGI:96176
Bos taurus HOXA4 VGNC VGNC:29912
Felis catus HOXA4 VGNC VGNC:80596
Rattus norvegicus HOXA4 RGD RGD:2814
Macaca mulatta HOXA4 VGNC VGNC:81326