2. Gene
  3. EHMT1 - euchromatic histone lysine methyltransferase 1 Gene

EHMT1 - euchromatic histone lysine methyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362078 | Gene type: protein coding

About EHMT1

Primary_assembly 3: 7,580,683-7,729,007 reverse strand.mRatBN7.2:CM026976.1

This gene has 5 transcripts (splice variants), 314 orthologues, 23 paralogues and is associated with 16 phenotypes. Biased expression in Thymus (RPKM 14.5), Adrenal (RPKM 113.7) and 9 other tissues.

Summary

Predicted to enable several functions, including C2H2 zinc finger domain binding activity; histone-lysine N-methyltransferase activity; and p53 binding activity. Involved in response to fungicide. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in Kleefstra syndrome and Kleefstra syndrome 1. Orthologous to human EHMT1 (euchromatic histone lysine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

EHMT1 Products(1)

mRNA Protein Name
NM_001108572.1 NP_001102042.1 histone-lysine N-methyltransferase EHMT1

EHMT1 Protein Structure

EHMT_ZBD

EHMT_ZBD: cd20905 (527 - 657)

Ank_2

Ank_2: pfam12796 (753 - 847)

ANK

ANK: sd00045 (785 - 814)

ANK

ANK: sd00045 (816 - 847)

Ank_2

Ank_2: pfam12796 (821 - 914)

ANK

ANK: sd00045 (849 - 881)

ANK

ANK: sd00045 (883 - 914)

Ank_2

Ank_2: pfam12796 (888 - 980)

ANK

ANK: sd00045 (916 - 947)

ANK

ANK: sd00045 (949 - 980)

SET_EHMT1

SET_EHMT1: cd10535 (1047 - 1277)

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  • 1310 a.a.
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase EHMT1

euchromatic histone methyltransferase 1

euchromatic histone-lysine N-methyltransferase 1

histone-lysine N-methyltransferase EHMT1-like

histone-lysine N-methyltransferase, H3 lysine-9 specific 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12583 A-366 Inhibitor 98.02% Unkown
HY-13808 UNC 0631 Inhibitor 98.35% Unkown
HY-13807 UNC0646 Inhibitor 99.82% Unkown
HY-111904 EHMT2-IN-2 Inhibitor ≥99.0% Unkown
HY-111778 EHMT2-IN-1 Inhibitor 99.85% Unkown
HY-148817 WDR5-0102 Inhibitor 97.02% Unkown
HY-RS04227 EHMT1 Human Pre-designed siRNA Set A / Unkown
HY-RS04228 Ehmt1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS04229 EHMT1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens EHMT1 NCBI NCBI:79813