Mbd3 - methyl-CpG binding domain protein 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362834

Summary

Predicted to enable chromatin binding activity and methyl-CpG binding activity. Involved in several processes, including animal organ development; regulation of DNA methylation; and response to estradiol. Predicted to be located in cytoplasm; heterochromatin; and nucleus. Predicted to be part of NuRD complex. Biomarker of transient cerebral ischemia and visual epilepsy. Orthologous to human MBD3 (methyl-CpG binding domain protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Mbd3 Products (1)

mRNA Protein Name
NM_001108735.1 NP_001102205.1 methyl-CpG-binding domain protein 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in embryonic organ development IEP
IEP: Inferred from expression pattern
12672019 RGD
involved in epigenetic regulation of gene expression IEP
IEP: Inferred from expression pattern
20735989 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
22109888 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
16702315 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22109888 RGD
involved in ventricular cardiac muscle tissue development IEP
IEP: Inferred from expression pattern
20735989 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methyl-CpG-binding domain protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08183 MBD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19351 Mbd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25842 Mbd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99506 Tamrintamab 98.51% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbd3 NCBI NCBI:53615