Foxc1 - forkhead box C1 Gene

Predicted to enable DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including animal organ development; cellular response to growth factor stimulus; and positive regulation of cell differentiation. Predicted to act upstream of or within several processes, including animal organ development; cell surface receptor signaling pathway; and vasculature development. Predicted to be located in cytosol; heterochromatin; and nucleoplasm. Human ortholog(s) of this gene implicated in Axenfeld-Rieger syndrome; Axenfeld-Rieger syndrome type 3; anterior segment dysgenesis 3; and glaucoma. Orthologous to human FOXC1 (forkhead box C1). [provided by Alliance of Genome Resources, Apr 2022]