Clcf1 - cardiotrophin-like cytokine factor 1 Gene

Predicted to enable cytokine activity. Predicted to contribute to ciliary neurotrophic factor receptor binding activity. Predicted to be involved in several processes, including positive regulation of B cell activation; positive regulation of astrocyte differentiation; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to act upstream of or within B cell differentiation. Predicted to be part of CNTFR-CLCF1 complex and CRLF-CLCF1 complex. Predicted to be active in extracellular region. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 2. Orthologous to human CLCF1 (cardiotrophin like cytokine factor 1). [provided by Alliance of Genome Resources, Apr 2022]