HMGCR - 3-hydroxy-3-methylglutaryl-CoA reductase Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 479182

About HMGCR

Primary_assembly 3: 30,898,248-30,921,069 reverse strand.ROS_Cfam_1.0:CM025102.1

This gene has 3 transcripts (splice variants) and 206 orthologues.

HMGCR Products (6)

mRNA Protein Name
XM_038661035.1 XP_038516963.1 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X1
XM_038661037.1 XP_038516965.1 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X2
XM_038661038.1 XP_038516966.1 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X3
XM_038661035.1 XP_038516963.1 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X1
XM_038661038.1 XP_038516966.1 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X3
XM_038661037.1 XP_038516965.1 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X2

HMGCR Protein Structure

2A060605

2A060605: TIGR00920 (45 - 932)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 933 a.a.
Protein Preferred Names Protein Names

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17504 Rosuvastatin Calcium 99.77% Yes
HY-17504B Rosuvastatin Sodium 99.91% Yes
HY-119695A Simvastatin acid ammonium Inhibitor 99.70% Unkown
HY-115292 Simvastatin hydroxy acid sodium Inhibitor 99.86% Unkown
HY-119695 Simvastatin acid Inhibitor 95.51% Unkown
HY-119695B Simvastatin acid calcium hydrate Inhibitor / Unkown

Pre-clinical Phase

Bioactive Molecules (38)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-107855 DL-Mevalonolactone 99.15% Unkown
HY-15483 DY131 99.72% Unkown
HY-N0466 Rebaudioside A 98.0% Unkown
HY-N6712 Thiolutin Inhibitor 99.27% Unkown
HY-N0686 Pseudoprotodioscin Inhibitor 99.17% Unkown
HY-111355 Cholesterol sulfate 99.71% Unkown
HY-135700 Mevalonolactone 98.0% Unkown
HY-N0430A Coptisine Sulfate 99.37% Unkown
HY-17504R Rosuvastatin Calcium (Standard) 99.94% Unkown
HY-114316 HMG499 Inhibitor 96.12% Unkown
HY-142026 Vitisin A 96% Unkown
HY-17504BS1 Rosuvastatin-d6 sodium Inhibitor 99.9% Unkown
HY-106281 Bemfivastatin Inhibitor 99.48% Unkown
HY-106281A Bemfivastatin hemicalcium Inhibitor 98.00% Unkown
HY-N0430 Coptisine / Unkown
HY-N11637 Ganoderenic acid K Inhibitor 99.64% Unkown
HY-RS06238 HMGCR Human Pre-designed siRNA Set A / Unkown
HY-W740010 N-Desmethyl rosuvastatin disodium hydrate 99.1% Unkown
HY-17504BS2 Rosuvastatin-13C,d3 sodium / Unkown
HY-101873S Atorvastatin lactone-d5 Inhibitor / Unkown
HY-107855S2 DL-Mevalonolactone-13C / Unkown
HY-107855S4 DL-Mevalonolactone-13C2 / Unkown
HY-115292S Simvastatin hydroxy acid-d6 sodium Inhibitor / Unkown
HY-116241 L-157012 Inhibitor / Unkown
HY-119695AS1 Simvastatin acid-d9 ammonium Inhibitor / Unkown
HY-147195 QH536 Inhibitor / Unkown
HY-171823 PROTAC HMGCR Degrader-1 Degrader / Unkown
HY-181134 PROTAC HMGCR Degrader-2 / Unkown
HY-184354 NO-Pravastatin / Unkown
HY-N11637A (Z)-Ganoderenic acid K Control / Unkown
HY-N16439 Phenicin Inhibitor / Unkown
HY-P11881 IUB288 / Unkown
HY-RS06239 Hmgcr Mouse Pre-designed siRNA Set A / Unkown
HY-RS06240 Hmgcr Rat Pre-designed siRNA Set A / Unkown
HY-W752587 DL-Mevalonolactone-d4 / Unkown
HY-107855R DL-Mevalonolactone (Standard) / Unkown
HY-119695S Simvastatin acid-d6 Inhibitor / Unkown
HY-136345A 3'-Hydroxy simvastatin 99.71% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HMGCR NCBI NCBI:3156