Bemfivastatin hemicalcium
Based on 1 Customer Validation
Bemfivastatin (PPD 10558) hemicalcium is an orally active HMG-CoA Reductase (HMGCR) inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extraction and reduces blood lipid levels. Bemfivastatin hemicalcium can be used for research of metabolic disease, such as hypercholesterolemia.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 805241-64-9
- Formula: C34H37FN2O6.1/2Ca
- Molecular Weight:607.74
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Bemfivastatin hemicalcium (12.5-50 mg/kg, p.o., daily from day 6 to 18) causes mortality, abortions and body weight reduction in pregnant rabbits[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Pregnant rabbits[1]
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Dosage:12.5, 25 and 50 mg/kg
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Administration:Orally administration, daily from day 6 to 18
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Result:Showed 1 rabbit death at 25 mg/kg and 7 at 50 mg/kg.
Showed 2 rabbit abortions 25 mg/kg and 6 at 50 mg/kg.
Showed reduction in gestation body weight and decreased food consumption.
Chemical Information
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CAS No. 805241-64-9
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Appearance Solid
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Molecular Weight 607.74
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Formula C34H37FN2O6.1/2Ca
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Color White to off-white
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SMILES
[O-]C(C[C@H](O)C[C@H](O)CCN1C(C2=CC=C(F)C=C2)=C(C3=CC=CC=C3)C(C(NC4=CC=C(CO)C=C4)=O)=C1C(C)C)=O.[Ca+2].[1/2]
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Synonyms
PPD 10558 hemicalcium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)