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Cat. No.: HY-115292S

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Simvastatin hydroxy acid-d₆sodium

(Synonyms: Tenivastatin-d₆ sodium; Simvastatin impurity A-d₆ sodium)

Simvastatin hydroxy acid-d₆ sodium (Tenivastatin-d₆ sodium) is the deuterium labeled Simvastatin hydroxy acid sodium (HY-115292). Simvastatin hydroxy acid (Tenivastatin) sodium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin hydroxy acid sodium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin hydroxy acid sodium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

For research use only. We do not sell to patients.

CAS No.: 2747915-76-8
Formula: C₂₅H₃₃D₆NaO₆
Molecular Weight:464.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Simvastatin hydroxy acid-d₆sodium Chemical Structure

CAS No.: 2747915-76-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
- Application
Chemical Information
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Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2747915-76-8
Unlabeled Cas 101314-97-0
Molecular Weight 464.60
Formula C₂₅H₃₃D₆NaO₆
SMILES

CCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C(O[C@@H]1[C@@]2([H])C(C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(O[Na])=O)=C[C@H](C)C1)=O
Synonyms

Tenivastatin-d₆ sodium; Simvastatin impurity A-d₆ sodium
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.