3'-Hydroxy simvastatin
Based on 1 Customer Validation
3′-Hydroxy simvastatin is an oxidative metabolite of Simvastatin (HY-17502) produced by hepatic CYP450 metabolism, and is also the major terminal metabolite of Simvastatin in rats. 3′-Hydroxy simvastatin possesses HMG-CoA Reductase inhibitory activity. 3′-Hydroxy simvastatin is used in metabolism-related research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.71%
- CAS. Nr.: 1283861-33-5
- Formel: C25H38O6
- Molecular Weight:434.57
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Speicherung:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
(Rac)-3′-Hydroxy simvastatin is an isomer of 3′-Hydroxy simvastatin. 3′-Hydroxy simvastatin is generated from Simvastatin (HY-17502) via cytochrome P450-dependent oxidative metabolism in rat liver microsomes[1].
(Rac)-3′-Hydroxy simvastatin is an isomer of 3′-Hydroxy simvastatin. 3′-Hydroxy simvastatin exhibits 20% of the HMG-CoA reductase inhibitory potency of Simvastatin acid (HY-119695)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 1283861-33-5
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Appearance Solid
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Molecular Weight 434.57
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Formel C25H38O6
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Color White to off-white
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SMILES
[H][C@@]1([C@H](C=CC2=C[C@@H](C[C@@H]([C@@]21[H])OC(C(C)(C(O)C)C)=O)C)C)CC[C@@]3([H])OC(C[C@@H](C3)O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reinheit & Dokumentation
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Data Sheet (289 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
3'-Hydroxy simvastatin Related Classifications
HY-136345A Related Classifications
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