NPTX1 - neuronal pentraxin 1 Gene

Also Known as NP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4884

About NPTX1

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:80,466,834-80,476,607 (from NCBI)

This gene has 5 transcripts (splice variants), 264 orthologues and 5 paralogues. Biased expression in brain (RPKM 51.6) and adrenal (RPKM 2.1).

Summary

NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008]

NPTX1 Products (1)

mRNA Protein Name
NM_002522.4 NP_002513.2 neuronal pentraxin-1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27986928 GOA
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27986928 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NPTX1 Protein Structure

Pentaxin

Pentaxin: Pentaxin family (232 - 420)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 432 a.a.
Protein Preferred Names Protein Names

neuronal pentraxin-1

  • NP-I

Recombinant NPTX1 Proteins

Cat. No. Product Name Accession Purity
HY-P71169 NPTX1 Protein, Human (HEK293, His) Q15818 (Q23-N432) ≥ 95%, as determined by reducing SDS-PAGE.

NPTX1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P811355 NP1 Antibody WB, IHC-P Human, Mouse, Rat

Related Diseases

Diseases Alias
Wallerian Degeneration

  • Wallerian Degeneration Of The Pyramidal Tract
Central Precocious Puberty

  • Cpp

  • Gonadotropin-Dependant Precocious Puberty

  • Gonadotropin-Dependent Precocious Puberty

  • Precocious Puberty, Central
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09505 NPTX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19725 Nptx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26221 Nptx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NPTX1 VGNC VGNC:43933
Macaca mulatta NPTX1 VGNC VGNC:75391
Felis catus NPTX1 VGNC VGNC:99309
Rattus norvegicus NPTX1 RGD RGD:628894
Bos taurus NPTX1 VGNC VGNC:32218
Mus musculus NPTX1 MGD MGI:107811
Others NPTX1 NCBI