Dut - deoxyuridine triphosphatase Gene

Also Known as Dutp; PIP4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 497778

Summary

Enables several functions, including dUTP diphosphatase activity; peroxisome proliferator activated receptor binding activity; and pyrimidine deoxyribonucleotide binding activity. Involved in several processes, including liver development; pyrimidine deoxyribonucleotide metabolic process; and regulation of protein-containing complex assembly. Located in cytosol and nucleus. Orthologous to human DUT (deoxyuridine triphosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Dut Products (2)

mRNA Protein Name
NM_001040271.2 NP_001035361.1 deoxyuridine 5'-triphosphate nucleotidohydrolase isoform 2
NM_053592.3 NP_446044.1 deoxyuridine 5'-triphosphate nucleotidohydrolase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables dUTP diphosphatase activity IDA
IDA: Inferred from direct assay
1315924 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
3032103 RGD
enables peroxisome proliferator activated receptor binding IPI
IPI: Inferred from physical interaction
8910358 RGD
enables pyrimidine deoxyribonucleotide binding IDA
IDA: Inferred from direct assay
3032103 RGD
enables signaling receptor inhibitor activity IDA
IDA: Inferred from direct assay
8910358 RGD
Biological Process GO Annotation Evidence References Source
involved in dUMP biosynthetic process IDA
IDA: Inferred from direct assay
1315924 RGD
involved in dUTP catabolic process IDA
IDA: Inferred from direct assay
1315924 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
11121581 RGD
involved in regulation of protein-containing complex assembly IDA
IDA: Inferred from direct assay
8910358 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
2841940 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deoxyuridine 5'-triphosphate nucleotidohydrolase

  • PPAR-interacting protein 4

  • dUTP pyrophosphatase

  • dUTPase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04071 DUT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W243971 DUT-5 / Unkown
HY-W243979 DUT-8(Co) / Unkown
HY-W249558 DUT-8(Cu) / Unkown
HY-W249567 DUT-8(Ni) / Unkown
HY-RS20235 Dut Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26742 Dut Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dut NCBI NCBI:1854