Kmt2c - lysine methyltransferase 2C Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 502710

Summary

Predicted to enable Histone Methyltransferase activity (H3-K4 specific). Predicted to be involved in histone H3-K4 monomethylation. Predicted to act upstream of or within several processes, including eyelid development in camera-type eye; positive regulation of fibroblast proliferation; and single fertilization. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. Human ortholog(s) of this gene implicated in Klatskin's tumor; Kleefstra syndrome 2; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human KMT2C (lysine methyltransferase 2C). [provided by Alliance of Genome Resources, Apr 2022]

Kmt2c Products (20)

mRNA Protein Name
XM_039108981.1 XP_038964909.1 histone-lysine N-methyltransferase 2C isoform X19
XM_039108982.1 XP_038964910.1 histone-lysine N-methyltransferase 2C isoform X20
XM_039108963.1 XP_038964891.1 histone-lysine N-methyltransferase 2C isoform X1
XM_039108969.1 XP_038964897.1 histone-lysine N-methyltransferase 2C isoform X7
XM_039108966.1 XP_038964894.1 histone-lysine N-methyltransferase 2C isoform X4
XM_039108971.1 XP_038964899.1 histone-lysine N-methyltransferase 2C isoform X10
XM_039108965.1 XP_038964893.1 histone-lysine N-methyltransferase 2C isoform X3
XM_039108974.1 XP_038964902.1 histone-lysine N-methyltransferase 2C isoform X13
XM_039108978.1 XP_038964906.1 histone-lysine N-methyltransferase 2C isoform X17
XM_039108979.1 XP_038964907.1 histone-lysine N-methyltransferase 2C isoform X18
XM_008762670.3 XP_008760892.2 histone-lysine N-methyltransferase 2C isoform X9
XM_039108975.1 XP_038964903.1 histone-lysine N-methyltransferase 2C isoform X14
XM_039108973.1 XP_038964901.1 histone-lysine N-methyltransferase 2C isoform X12
XM_039108972.1 XP_038964900.1 histone-lysine N-methyltransferase 2C isoform X11
XM_039108967.1 XP_038964895.1 histone-lysine N-methyltransferase 2C isoform X5
XM_039108964.1 XP_038964892.1 histone-lysine N-methyltransferase 2C isoform X2
XM_039108976.1 XP_038964904.1 histone-lysine N-methyltransferase 2C isoform X15
XM_039108977.1 XP_038964905.1 histone-lysine N-methyltransferase 2C isoform X16
XM_039108968.1 XP_038964896.1 histone-lysine N-methyltransferase 2C isoform X6
XM_039108970.1 XP_038964898.1 histone-lysine N-methyltransferase 2C isoform X8

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
27207907 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase 2C

similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)

  • lysine (K)-specific methyltransferase 2C

  • myeloid/lymphoid or mixed-lineage leukemia 3-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07403 KMT2C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26552 Kmt2c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20048 Kmt2c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kmt2c NCBI NCBI:58508