E2f6 - E2F transcription factor 6 Gene

Also Known as EMA; E2F6a; E2F6b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50496

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within regulation of transcription involved in G1/S transition of mitotic cell cycle. Predicted to be located in nucleoplasm. Predicted to be part of MLL1 complex and RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human E2F6 (E2F transcription factor 6). [provided by Alliance of Genome Resources, Apr 2022]

E2f6 Products (1)

mRNA Protein Name
NM_033270.2 NP_150373.2 transcription factor E2F6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15574595 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
15574595 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18667754 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
18667754 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
15574595 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor E2F6

  • E2F-6

  • E2F-binding site-modulating activity protein

  • transcriptional repressor E2F6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04115 E2F6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20270 E2f6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26778 E2f6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens E2f6 NCBI NCBI:1876